Question 1

Lamisil is an allylamine used to treat dermatomycoses. Lamisilʹs method of action is similar to that of

Accepted Answer

A)   polymyxin B.
B)   echinocandins.
C)   bacitracin.
D)   azole antibiotics.
E)   griseofulvin.F) A) and D)
G) A) and E)

Question 2

An antibiotic that attacks the LPS layer would be expected to have a narrow spectrum of activity.

Accepted Answer

A) True 
 B)False

Question 3

Which of the following antibiotics is recommended for use against gram -negative bacteria?

Accepted Answer

A)   polymyxin
B)   penicillin
C)   bacitracin
D)   cephalosporin
E)   polyenesF) C) and D)
G) A) and B)

Question 4

Figure 20.4  The structures of the influenza drug Tamiflu and sialic acid, the substrate for influenza virusʹs neuramidase, are shown in Figure 20.4. What is the method of action of Tamiflu?

Accepted Answer

A)   inhibits plasma membrane synthesis
B)   competitive inhibition
C)   inhibits synthesis of neuramidase
D)   inhibits cell wall synthesis
E)   prevents synthesis of virus spikesF) C) and E)
G) B) and C)

Question 5

Which of the following statements about drug resistance is FALSE?

Accepted Answer

A)   It may be transferred from one bacterium to another during conjugation.
B)   It may be carried on a plasmid.
C)   It may be due to enzymes that degrade some antibiotics.
D)   It is found only in gram-negative bacteria.
E)   It may be due to increased uptake of a drug.F) A) and B)
G) A) and E)

Question 6

Table 20.2
The following results were obtained from a disk-diffusion test for microbial susceptibility to antibiotics. Staphylococcus aureus was the test organism.   Antibiotic  Zone of Inhibition A3 mmB7 mmC0 mmD10 mm\begin{array} { | l | l | } \hline  { 	ext { Antibiotic } } & 	ext { Zone of Inhibition } \\hline \mathrm { A } & 3 \mathrm {~mm} \\hline \mathrm { B } & 7 \mathrm {~mm} \\hline \mathrm { C } & 0 \mathrm {~mm} \\hline \mathrm { D } & 10 \mathrm {~mm} \\hline\end{array} Antibiotic ABCD​ Zone of Inhibition 3 mm7 mm0 mm10 mm​​ 
-In Table 20.2, which antibiotic would be most useful for treating a Salmonella infection?

Accepted Answer

A)   A
B)   B
C)   C
D)   D
E)   The answer cannot be determined based on the information provided. F) None of the above
G) All of the above

Question 7

Which of the following is mismatched?

Accepted Answer

A)   Fleming  initial identification of penicillinʹs effect on gram-positive microbial growth
B)   Florey and Chain  identification of Penicillium as the producer of penicillin
C)   Kirby and Bauer  disc-diffusion method
D)   Ehrlich  ʺmagic bulletʺ theory
E)   None of these is mismatched.F) A) and C)
G) A) and D) B

Question 8

Antiviral drugs target viral processes that occur during viral infection.

Accepted Answer

A) True 
 B)False  True

Question 9

The antimicrobial drugs with the broadest spectrum of activity are

Accepted Answer

A)   chloramphenicol.
B)   tetracyclines.
C)   penicillin G.
D)   macrolides.
E)   aminoglycosides.F) None of the above
G) B) and D)

Question 10

Which compound would be the most useful to treat candidiasis?

Accepted Answer

A)   thymine
B)   flucytosine
C)   penicillin
D)   uracil
E)   guanineF) B) and D)
G) D) and E) B

Question 11

Community-acquired MRSA is typically more virulent than health care-associated MRSA.

Accepted Answer

A) True 
 B)False

Question 12

Which of the following drugs does NOT act by competitive inhibition?

Accepted Answer

A)   trimethoprim
B)   ethambutol
C)   sulfonamide
D)   streptomycin
E)   isoniazidF) A) and E)
G) A) and C)

Question 13

Which of the following statements is FALSE?

Accepted Answer

A)   Interferon inhibits glycolysis.
B)   Acyclovir inhibits DNA synthesis.
C)   Azoles inhibit plasma membrane synthesis.
D)   Amantadine inhibits the release of viral nucleic acid.
E)   Fluoroquinolone inhibits DNA synthesis.F) B) and D)
G) C) and E)

Question 14

Table 20.1
The following data were obtained from a broth dilution test.   Concentration of AntibioticX  Growth  Growth in  Subculture 2μg/ml++10μg/ml−+15μg/ml−−25μg/ml−−\begin{array}{|l|l|l|}\hline	ext { Concentration of AntibioticX } & 	ext { Growth } & \frac{	ext { Growth in }}{	ext { Subculture }} \\hline 2 \mu \mathrm{g} / \mathrm{ml} & + & + \\hline 10 \mu \mathrm{g} / \mathrm{ml} & - & + \\hline 15 \mu \mathrm{g} / \mathrm{ml} & - & - \\hline 25 \mu \mathrm{g} / \mathrm{ml} & - & - \ \hline\end{array} Concentration of AntibioticX 2μg/ml10μg/ml15μg/ml25μg/ml​ Growth +−−−​ Subculture  Growth in ​++−−​​ 
-In Table 20.1, the minimal inhibitory concentration of antibiotic X is

Accepted Answer

A)   25 ?g/ml.
B)   15 ?g/ml.
C)   2 ?g/ml.
D)   10 ?g/ml.
E)   The answer cannot be determined based on the information provided. F) D) and E)
G) B) and D)

Question 15

Penicillin does not directly kill bacteria. Why, then, is it considered to be bacteriocidal?

Accepted Answer

Penicillin is considered bactericidal be...

Question 16

Antimicrobial peptides (AMPs)  frequently work by

Accepted Answer

A)   disrupting the plasma membrane.
B)   hydrolyzing peptidoglycan.
C)   complementary base pairing with DNA.
D)   inhibiting cell-wall synthesis.
E)   inhibiting protein synthesis.F) B) and D)
G) D) and E)

Question 17

Which of the following does NOT constitute an advantage of using two antibiotics together?

Accepted Answer

A)   It lessens the toxicity of individual drugs.
B)   It allows treatment to be provided prior to diagnosis.
C)   It can prevent drug resistance.
D)   Two are always twice as effective as one.
E)   All of these are advantages of using two antibiotics together.F) B) and E)
G) All of the above

Question 18

The antibiotic actinomycin D binds between adjacent G-C pairs, thus interfering with

Accepted Answer

A)   translation.
B)   peptide bond formation.
C)   cellular respiration.
D)   plasma membrane function.
E)   transcription.F) C) and D)
G) B) and E)

Question 19

Explain the difficulties in developing antiviral drugs against DNA viruses, when compared to RNA viruses.

Accepted Answer

Developing antiviral drugs against DNA v...

Question 20

Which of the following antibiotics are used to treat fungal infections? 1. aminoglycosides
2)  cephalosporins
3)  griseofulvin
4)  polyenes
5)  bacitracin

Accepted Answer

A)   1, 2, and 3
B)   3, 4, and 5
C)   3 and 4
D)   4 and 5
E)   All of these antibiotics are used to treat fungal infections.F) A) and B)
G) All of the above

Exam 20: Antimicrobial Drugs

Lamisil is an allylamine used to treat dermatomycoses. Lamisilʹs method of action is similar to that of

Correct Answer
verified

An antibiotic that attacks the LPS layer would be expected to have a narrow spectrum of activity.

Correct Answer
verified

Which of the following antibiotics is recommended for use against gram -negative bacteria?

Correct Answer
verified

Figure 20.4 The structures of the influenza drug Tamiflu and sialic acid, the substrate for influenza virusʹs neuramidase, are shown in Figure 20.4. What is the method of action of Tamiflu?

Correct Answer
verified

Which of the following statements about drug resistance is FALSE?

Correct Answer
verified

Correct Answer
verified

Which of the following is mismatched?

Correct Answer
verified
B

Antiviral drugs target viral processes that occur during viral infection.

Correct Answer
verified
True

The antimicrobial drugs with the broadest spectrum of activity are

Correct Answer
verified

Which compound would be the most useful to treat candidiasis?

Correct Answer
verified
B

Community-acquired MRSA is typically more virulent than health care-associated MRSA.

Correct Answer
verified

Which of the following drugs does NOT act by competitive inhibition?

Correct Answer
verified

Which of the following statements is FALSE?

Correct Answer
verified

Correct Answer
verified

Penicillin does not directly kill bacteria. Why, then, is it considered to be bacteriocidal?

Correct Answer
Answered by ExamLex AI
Penicillin is considered bactericidal be...
View Answer

Antimicrobial peptides (AMPs) frequently work by

Correct Answer
verified

Which of the following does NOT constitute an advantage of using two antibiotics together?

Correct Answer
verified

The antibiotic actinomycin D binds between adjacent G-C pairs, thus interfering with

Correct Answer
verified

Explain the difficulties in developing antiviral drugs against DNA viruses, when compared to RNA viruses.

Correct Answer
Answered by ExamLex AI
Developing antiviral drugs against DNA v...
View Answer

Which of the following antibiotics are used to treat fungal infections? 1. aminoglycosides 2) cephalosporins 3) griseofulvin 4) polyenes 5) bacitracin

Correct Answer
verified

Exam 20: Antimicrobial Drugs

Lamisil is an allylamine used to treat dermatomycoses. Lamisilʹs method of action is similar to that of

Correct AnswerverifiedShow Answer

An antibiotic that attacks the LPS layer would be expected to have a narrow spectrum of activity.

Correct AnswerverifiedShow Answer

Which of the following antibiotics is recommended for use against gram -negative bacteria?

Correct AnswerverifiedShow Answer

Figure 20.4 The structures of the influenza drug Tamiflu and sialic acid, the substrate for influenza virusʹs neuramidase, are shown in Figure 20.4. What is the method of action of Tamiflu?

Correct AnswerverifiedShow Answer

Which of the following statements about drug resistance is FALSE?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Which of the following is mismatched?

Correct AnswerverifiedB

Antiviral drugs target viral processes that occur during viral infection.

Correct AnswerverifiedTrue

The antimicrobial drugs with the broadest spectrum of activity are

Correct AnswerverifiedShow Answer

Which compound would be the most useful to treat candidiasis?

Correct AnswerverifiedB

Community-acquired MRSA is typically more virulent than health care-associated MRSA.

Correct AnswerverifiedShow Answer

Which of the following drugs does NOT act by competitive inhibition?

Correct AnswerverifiedShow Answer

Which of the following statements is FALSE?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Penicillin does not directly kill bacteria. Why, then, is it considered to be bacteriocidal?

Correct AnswerAnswered by ExamLex AIPenicillin is considered bactericidal be...View AnswerShow Answer

Antimicrobial peptides (AMPs) frequently work by

Correct AnswerverifiedShow Answer

Which of the following does NOT constitute an advantage of using two antibiotics together?

Correct AnswerverifiedShow Answer

The antibiotic actinomycin D binds between adjacent G-C pairs, thus interfering with

Correct AnswerverifiedShow Answer

Explain the difficulties in developing antiviral drugs against DNA viruses, when compared to RNA viruses.

Correct AnswerAnswered by ExamLex AIDeveloping antiviral drugs against DNA v...View AnswerShow Answer

Which of the following antibiotics are used to treat fungal infections? 1. aminoglycosides 2) cephalosporins 3) griseofulvin 4) polyenes 5) bacitracin

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
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Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
B

Correct Answer
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True

Correct Answer
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Correct Answer
verified
B

Correct Answer
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Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
Answered by ExamLex AI
Penicillin is considered bactericidal be...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
Answered by ExamLex AI
Developing antiviral drugs against DNA v...
View Answer

Correct Answer
verified