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The field of genomics refers to _______.


A) the study of an organism's plasmids
B) the study of cellular, but not viral, genomes
C) the study of chromosomal DNA
D) the study of an organism's complete genome, including plasmid, mitochondrial, and chloroplast DNA

E) B) and C)
F) A) and D)

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The fundamental difference between an organism's genotype and its phenotype is that _______.


A) the phenotype refers to all of the genetic material in the organism, whereas the genotype represents only the genetic material that is expressed into proteins
B) the genotype refers to eukaryotic genes that contain both introns and exons, whereas phenotype refers to bacterial DNA that has only exons
C) the genotype refers to the organism's genes and the phenotype refers to the non-coding segments of DNA
D) the genotype refers to all of the genetic material in the organism, whereas the phenotype represents only the genetic material that is expressed into proteins

E) A) and D)
F) A) and C)

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The antiparallel arrangement within DNA molecules refers to _______.


A) each base bonding at the 1' position of the sugar
B) a purine always bonding to a pyrimidine
C) one helix strand that runs from the 5' to 3' direction and the other strand runs from the 3' to 5' direction
D) an original parent DNA strand and one newly synthesized DNA strand comprising a new DNA molecule

E) B) and C)
F) B) and D)

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A permanent, inheritable change in the genetic information is called ________.


A) translation
B) transcription
C) a mutation
D) an alteration
E) regeneration

F) B) and D)
G) C) and D)

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A mutation has occurred during DNA replication while the cell was preparing to divide. As a result of this, the codon ACU of mRNA has now become ACC. Interestingly, there is no change to the protein being made. Why not?


A) This is a silent mutation.
B) The original amino acid isoleucine was changed to leucine, but they are the same variation of amino acid so no change to the protein.
C) The mutation was ?xed, and even though the codon is now ACC the correct amino acid is put into place for the normal protein.
D) This is not a mutation that causes a big change, so there is no change to the protein being made.

E) B) and C)
F) C) and D)

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Which molecule is translated into an amino acid sequence?


A) Ribosomal RNA
B) Messenger RNA
C) Transfer RNA
D) Primer RNA
E) Ribozymes

F) B) and E)
G) A) and B)

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A primer comprised of _______ is needed at the origin of nucleotide addition.


A) polymerase III
B) polymerase I
C) helicase
D) RNA
E) DNA

F) B) and E)
G) A) and E)

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An unidenti?ed cell was found to contain introns and exons. It also expresses DNA polymerase and RNA polymerase. Although it exhibits a promoter region, it has no operons. You conclude that this cell _______.


A) is eukaryotic
B) is prokaryotic
C) is either a prokaryotic or eukaryotic cell
D) is actually a virus

E) B) and C)
F) C) and D)

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DNA photolyase, in the presence of visible light, can repair DNA damage due to ultraviolet radiation.

A) True
B) False

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All mutations are not beneficial to the cell.

A) True
B) False

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Repressible operons are normally turned on in the cell.

A) True
B) False

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If the wild type DNA sequence reads THE CAT ATE THE BIG RAT, what type of mutation would change the sequence to THE CAT ATA ETH EBI GRA T?


A) Missense
B) Nonsense
C) Insertion
D) Deletion
E) Silent

F) B) and C)
G) A) and D)

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Okazaki fragments are attached to the growing end of the lagging strand by _______.


A) DNA ligase
B) DNA polymerase
C) DNA helicase
D) DNA gyrase
E) primase

F) A) and E)
G) A) and B)

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The lactose repressor _______.


A) is transcribed with the structural lac genes
B) is activated by binding lactose
C) is inactivated by binding lactose
D) requires lactose for its transcription

E) A) and B)
F) A) and C)

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The expression of genetic traits is referred to as the organism's ______.


A) genome
B) genotype
C) proteome
D) phenotype
E) proteotype

F) B) and D)
G) B) and C)

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Repressible operons require that ______ binds to the repressor protein before it can bind to the operator.


A) the product
B) a cofactor
C) a coenzyme
D) the substrate
E) the reactant

F) A) and D)
G) B) and D)

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Which of the following is not true of transposons?


A) They can change pigmentation.
B) They can replace damaged DNA.
C) They can transfer drug resistance.
D) They can change the genome.
E) They are always part of plasmids.

F) B) and E)
G) None of the above

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The jumping of a gene from one location to another is done by ________.


A) conjugation
B) transposons
C) transformation
D) transduction
E) transmission

F) B) and C)
G) All of the above

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A screening system called the _______ test is used for detecting chemicals with carcinogenic potential.


A) Koch
B) Ames
C) mutation
D) cancer
E) Iowa

F) A) and E)
G) C) and E)

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Streptomycin, an aminoglycoside, inhibits protein synthesis _______.


A) by binding to the tRNA preventing peptide bond formation between amino acids
B) by binding to the ribosome, preventing translocation due to interference with the attachment of mRNA
C) by preventing the formation of the initiation complex
D) by interfering with both the initiation and elongation stages of translation

E) B) and C)
F) A) and D)

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