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Steroid hormones


A) bind to membrane receptors.
B) diffuse easily through the plasma membrane.
C) act by activating cAMP.
D) are inactivated by phosphodiesterase.
E) are water soluble.

F) A) and D)
G) C) and D)

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Most endocrine glands communicate with their target tissues using _____ signals.


A) frequency-modulated
B) amplitude-modulated
C) pitch-modulated
D) resonance-modulated

E) C) and D)
F) A) and B)

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Which of the following statements regarding hormone transport and distribution is FALSE?


A) Only free hormones can diffuse through capillary walls and bind to target tissues.
B) Hormones can be transported free in the plasma or bound to plasma proteins.
C) Plasma protein concentration has no influence on free hormone concentration.
D) Hormones bind only to certain types of plasma proteins.
E) All of the statements are true.

F) C) and D)
G) B) and E)

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C

In general, the response of target cells to endocrine stimulation is _______ than their response to nervous stimulation.


A) faster and briefer
B) slower and more prolonged
C) more accurate
D) more restricted to a small area of the body
E) more intense

F) A) and B)
G) B) and E)

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Match the chemical signal with the appropriate description. -neuropeptide


A) chemicals produced by neurons that function as hormones
B) chemicals that act locally on nearby cells
C) chemical secreted by presynaptic terminal
D) influences same cell type from which it is secreted
E) chemical secreted into blood by specialized cells; travels some distance to target tissues

F) C) and E)
G) C) and D)

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In general, lipid-soluble hormones exhibit which type(s) of hormone secretion pattern(s) ?


A) chronic hormone secretion
B) chronic and acute hormone secretion
C) acute and episodic hormone secretion
D) episodic hormone secretion
E) chronic and episodic hormone secretion

F) A) and D)
G) A) and E)

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Increased testosterone levels reduce the secretion of gonadotropin-releasing hormone from the anterior pituitary. This is an example of


A) inhibition of hormone release by humoral stimuli
B) inhibition of hormone release by neural stimuli
C) inhibition of hormone release by external stimuli
D) inhibition of hormonal release by environmental stimuli
E) inhibition of hormone release by hormonal stimuli

F) C) and E)
G) All of the above

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Hormones act on specific tissues called _______ tissues.

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Match the description with the type of receptor model. -cyclic AMP or cyclic GMP involved


A) nuclear receptor model
B) membrane-bound receptor model

C) A) and B)
D) undefined

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Match the description with the type of receptor model. -used by most lipid-soluble hormones


A) nuclear receptor model
B) membrane-bound receptor model

C) A) and B)
D) undefined

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Phosphodiesterase functions


A) as a membrane-bound receptor molecule.
B) to inactivate cyclic AMP.
C) to attach phosphate groups to enzymes.
D) to combine GTP with cyclic AMP.
E) activates cGMP.

F) A) and E)
G) A) and D)

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B

All of the following are reasons why some hormones need assistance to travel in the blood except


A) They are small enough to be easily digested by blood enzymes.
B) They are easily filtered from the blood into the kidney tubules.
C) They have low solubility in blood plasma due to their chemical nature.
D) They cannot dissolve in the blood because they are water-soluble.

E) All of the above
F) A) and B)

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Which intracellular mediator is directly activated by the binding of a water-soluble hormone to a membrane receptor?


A) cGMP
B) cAMP
C) calmodulin
D) phospholipase C

E) A) and D)
F) A) and C)

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What type of chemical messenger is released from neurons to activate an adjacent cell?


A) paracrine
B) neurotransmitter
C) autocrine
D) endocrine

E) B) and D)
F) B) and C)

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Blood chemistry changes are examples of ______ stimuli, whereas sympathetic nervous system impulses are examples of _______ stimuli for hormone release.


A) neural; humoral
B) positive; negative
C) Negative; positive
D) humoral; neural

E) A) and B)
F) All of the above

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Emily is in labor with her first child. The amplitude-modulated system would show her oxytocin levels


A) to have a weak signal.
B) to have a moderate signal.
C) to have a strong signal.
D) too weak to measure.

E) A) and B)
F) A) and C)

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How do hormones and target cells recognize one another?


A) by signs
B) by the location of the target cells
C) by the presence of specific receptor molecules on the target cells
D) by the function of the target cells
E) by the location of the hormones

F) None of the above
G) A) and E)

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Match the chemical signal with the appropriate description. -neurotransmitter


A) chemicals produced by neurons that function as hormones
B) chemicals that act locally on nearby cells
C) chemical secreted by presynaptic terminal
D) influences same cell type from which it is secreted
E) chemical secreted into blood by specialized cells; travels some distance to target tissues

F) A) and B)
G) A) and C)

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Match the description with the type of receptor model. -messenger RNA synthesis regulated


A) nuclear receptor model
B) membrane-bound receptor model

C) A) and B)
D) undefined

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A

What type of hormone-receptor action allows insulin to move glucose into cells?


A) activation of cGMP
B) activation of adenylate cyclase
C) direct alteration of intracellular enzymes
D) phosphorylation of intracellular proteins

E) A) and B)
F) A) and C)

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