Question 1

What is the consequence for cells when the functioning TP53 gene is lost as a result of mutation?

Accepted Answer

A)   Cells undergo apoptosis.
B)   Cells escape apoptosis.
C)   Cells receive less oxygen.
D)   Cells adhere more readily.E) A) and B)
F) C) and D)

Question 2

Match the phrases with the corresponding terms.
-Radiation

Accepted Answer

A)  Is the process of cancer cell growth.
B)  Is used to kill cancer cells while minimizing damage to normal structures.
C)  Is guided by molecular analysis in specific diseases.
D)  Takes advantage of specific vulnerabilities in specific cancer cells.
E)  Provides a framework to determine treatment.F) A) and D)
G) C) and E)

Question 3

Which cancer originates from connective tissue?

Accepted Answer

A)   Osteogenic sarcoma
B)   Basal cell carcinoma
C)   Multiple myeloma
D)   AdenocarcinomaE) All of the above
F) A) and D)

Question 4

What is the major virus involved in the development of cervical cancer?

Accepted Answer

A)   Herpes simplex virus type 6
B)   Herpes simplex virus type 2
C)   Human papillomavirus
D)   Human immunodeficiency virusE) A) and D)
F) A) and B) C

Question 5

Match the organism factor with the cancer it causes.
-Cervical cancer

Accepted Answer

A)  HPV
B)  Human herpesvirus (HHV)  8
C)  Hepatis B virus (HBV) 
D)  Helicobacter pyloriE) All of the above
F) None of the above

Question 6

The survival rate for stage IV Hodgkin disease can be as high as:

Accepted Answer

A)   99%
B)   70%
C)   40%
D)   20%E) None of the above
F) A) and D)

Question 7

Burkitt lymphomas designate a chromosome that has a piece of chromosome 8 fused to a piece of chromosome 14.This is an example of which mutation of normal genes to oncogenes?

Accepted Answer

A)   Point mutation
B)   Chromosome translocation
C)   Gene amplification
D)   Chromosome fusionE) All of the above
F) A) and B)

Question 8

By what process do cancer cells multiply in the absence of external growth signals?

Accepted Answer

A)   Proto-oncogene
B)   Autocrine stimulation
C)   Reliance on caretaker genes
D)   PleomorphologyE) B) and D)
F) All of the above

Question 9

Which statement concerning benign tumors is true?

Accepted Answer

A)   The resulting pain is severe.
B)   Benign tumors are not encapsulated.
C)   Benign tumors are fast growing.
D)   The cells are well-differentiated.E) None of the above
F) C) and D)

Question 10

What cellular characteristics are affected by anaplasia? (Select all that apply.)

Accepted Answer

A)   Size
B)   Ability to differentiate
C)   Life expectancy
D)   Tissue structure
E)   ShapeF) B) and C)
G) C) and D) A,B,D,E

Question 11

Which cancers are all associated with chronic inflammation?

Accepted Answer

A)   Brain, muscle, and endocrine
B)   Colon, thyroid gland, and urinary bladder
C)   Bone, blood cells, and liver
D)   Eye, tracheal, and kidneyE) B) and C)
F) A) and D)

Question 12

Which gastrointestinal tract condition can be an outcome of both chemotherapy and radiation therapy?

Accepted Answer

A)   Increased cell turnover
B)   Constipation
C)   Stomatitis
D)   Bloody stoolE) C) and D)
F) B) and C)

Question 13

Which statement supports the hypothesis that intestinal polyps are benign neoplasms and the first stage in the development of colon cancer?

Accepted Answer

A)   Cancer cells accumulate slower than noncancer cells.
B)   An accumulation of mutations in specific genes is required for the development of cancer.
C)   Tumor invasion and metastasis progress more slowly in the gastrointestinal tract.
D)   Apoptosis is triggered by diverse stimuli, including excessive growth.E) A) and C)
F) All of the above

Question 14

Match the phrases with the corresponding terms.
-Angiogenesis

Accepted Answer

A)  Is the process of cancer cell growth.
B)  Is used to kill cancer cells while minimizing damage to normal structures.
C)  Is guided by molecular analysis in specific diseases.
D)  Takes advantage of specific vulnerabilities in specific cancer cells.
E)  Provides a framework to determine treatment.F) A) and B)
G) A) and C)

Question 15

Which term is used to describe a muscle cell showing a reduced ability to form new muscle while appearing highly disorganized?

Accepted Answer

A)   Dysplasia
B)   Hyperplasia
C)   Myoplasia
D)   AnaplasiaE) C) and D)
F) A) and B) D

Question 16

Which statement is true regarding pleomorphic cells?

Accepted Answer

A)   Pleomorphic cells are similar in size.
B)   They share a common shape.
C)   They are a result of anaplasia.
D)   Pleomorphic cells differentiate uniformly.E) A) and B)
F) A) and C)

Question 17

In childhood neuroblastoma,the N-myc oncogene undergoes which type of mutation of normal gene to oncogene?

Accepted Answer

A)   Point mutation
B)   Chromosome fusion
C)   Gene amplification
D)   Chromosome translocationE) None of the above
F) A) and B)

Question 18

What is the skin-related health risk induced by some types of chemotherapy?

Accepted Answer

A)   Infection
B)   Ultraviolet damage
C)   Pain
D)   ErythemaE) C) and D)
F) A) and C)

Question 19

Carcinoma refers to abnormal cell proliferation originating from which tissue origin?

Accepted Answer

A)   Blood vessels
B)   Epithelial cells
C)   Connective tissue
D)   Glandular tissueE) C) and D)
F) A) and D)

Question 20

Which statements concerning aging and the occurrence of cancer are true? (Select all that apply.)

Accepted Answer

A)   Decline in immunologic functions
B)   Predisposition to nutritional inadequacies
C)   Unwillingness to access health care services
D)   Reluctance to engage in cancer screenings
E)   Effects of immobility on the immune systemF) A) and B)
G) B) and D)

Exam 12: Cancer Biology

What is the consequence for cells when the functioning TP53 gene is lost as a result of mutation?

Correct AnswerverifiedShow Answer

Match the phrases with the corresponding terms. -Radiation

Correct AnswerverifiedShow Answer

Which cancer originates from connective tissue?

Correct AnswerverifiedShow Answer

What is the major virus involved in the development of cervical cancer?

Correct AnswerverifiedC

Match the organism factor with the cancer it causes. -Cervical cancer

Correct AnswerverifiedShow Answer

The survival rate for stage IV Hodgkin disease can be as high as:

Correct AnswerverifiedShow Answer

Burkitt lymphomas designate a chromosome that has a piece of chromosome 8 fused to a piece of chromosome 14.This is an example of which mutation of normal genes to oncogenes?

Correct AnswerverifiedShow Answer

By what process do cancer cells multiply in the absence of external growth signals?

Correct AnswerverifiedShow Answer

Which statement concerning benign tumors is true?

Correct AnswerverifiedShow Answer

What cellular characteristics are affected by anaplasia? (Select all that apply.)

Correct AnswerverifiedA,B,D,E

Which cancers are all associated with chronic inflammation?

Correct AnswerverifiedShow Answer

Which gastrointestinal tract condition can be an outcome of both chemotherapy and radiation therapy?

Correct AnswerverifiedShow Answer

Which statement supports the hypothesis that intestinal polyps are benign neoplasms and the first stage in the development of colon cancer?

Correct AnswerverifiedShow Answer

Match the phrases with the corresponding terms. -Angiogenesis

Correct AnswerverifiedShow Answer

Which term is used to describe a muscle cell showing a reduced ability to form new muscle while appearing highly disorganized?

Correct AnswerverifiedD

Which statement is true regarding pleomorphic cells?

Correct AnswerverifiedShow Answer

In childhood neuroblastoma,the N-myc oncogene undergoes which type of mutation of normal gene to oncogene?

Correct AnswerverifiedShow Answer

What is the skin-related health risk induced by some types of chemotherapy?

Correct AnswerverifiedShow Answer

Carcinoma refers to abnormal cell proliferation originating from which tissue origin?

Correct AnswerverifiedShow Answer

Which statements concerning aging and the occurrence of cancer are true? (Select all that apply.)

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
C

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
A,B,D,E

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
D

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified