Question 1

Mutations that convert proto-oncogenes to oncogenes are mutations that cause

Accepted Answer

A)   the gene to produce an altered gene product.
B)   underproduction of a normal gene product.
C)   overproduction of a normal gene product.
D)   an increase in the number of copies of the normal gene.
E)   all of these.F) B) and E)
G) All of the above

Question 2

Burkitt's lymphoma, chronic myelogenous leukemia, and many other leukemias are caused by chromosome ____________________.

Accepted Answer

The answer of Burkitt's lymphoma, chronic myelogenous leukemia, and many...

Question 3

The primary risk factor for cancer is ____________________.

Accepted Answer

The answer of The primary risk factor for cancer is...

Question 4

What is the role of oncogenes and tumor-suppressor genes, and how can mutations in these genes lead to cancer?

Accepted Answer

Oncogenes and tumor-suppressor genes pla...

Question 5

If retinoblastoma requires mutation in two copies of the RB gene, and familial cases inherit one such mutation, doesn't it seem unlikely that a second mutation would occur in a retinal cell at this specific gene? Yet 90 percent of those individuals who inherit one mutant RB gene develop a second mutation and retinoblastoma. Why does this occur with such a high frequency?

Accepted Answer

Retinoblastoma is a rare type of cancer ...

Question 6

The product of the RB tumor-suppressor gene is found in the cytoplasm.

Accepted Answer

A) True 
 B)False

Question 7

The drug Gleevec is most closely associated with which of the following molecules?

Accepted Answer

A)   DNA
B)   mRNA
C)   ATP
D)   NADH
E)   tRNAF) A) and D)
G) C) and D)

Question 8

Which one of the following statements about the BRCA1 gene for breast cancer is FALSE?

Accepted Answer

A)   It was discovered by Mary-Claire King and her colleagues.
B)   The gene is also linked to ovarian cancer.
C)   One mutated copy of BRCA1 is sufficient to cause cancer.
D)   Although only 1 in 200 females inherit it, 90 percent of them will develop breast cancer.
E)   It is located on the long arm of chromosome 17.F) A) and E)
G) None of the above

Question 9

It is estimated that 50 percent of all cancer deaths are related to behavior. Knowing the risks (and keeping in mind that you have a one in three chance of having cancer), do you feel inclined to alter your lifestyle to reduce your cancer risk? If so, what steps would you take? If not, why not?

Accepted Answer

Yes, I would definitely feel inclined to...

Question 10

Individuals have different ____________________ to environmental agents that cause cancer.

Accepted Answer

The answer of Individuals have different ____________________ to environmental agents...

Question 11

Which of the following is not a checkpoint in the cell cycle?

Accepted Answer

A)   The G1/S transition
B)   The S/G2 transition
C)   The G2/M transition
D)   Late metaphase
E)   The prophase/ metaphase transitionF) A) and D)
G) A) and C)

Question 12

Which of the following statements about retinoblastoma offers support for the idea that multiple mutations are needed in cancer?

Accepted Answer

A)   Noninherited cases involve both eyes and occur later in life.
B)   Noninherited cases involve both eyes and occur early in life.
C)   Inherited cases involve one eye and occur early in life.
D)   Inherited cases involve one eye and occur late in life.
E)   Noninherited cases involve one eye and occur later in life.F) D) and E)
G) C) and E)

Question 13

Specific aneuploidies are associated with various cancers.

Accepted Answer

A) True 
 B)False

Question 14

The genetic model of colon cancer states that development of colo-rectal cancer requires only one key mutation.

Accepted Answer

A) True 
 B)False

Question 15

According to the American Cancer Society, 30 pecent of all cancer deaths is due to

Accepted Answer

A)   ultraviolet light exposure.
B)   automobile exhaust.
C)   industrial pollutants.
D)   pesticide and herbicide exposure.
E)   smoking.F) C) and D)
G) A) and B)

Question 16

Hereditary nonpolyposis colon cancers (HNPCC)

Accepted Answer

A)   are caused by mutations in tumor-suppressor genes.
B)   are caused by mutations in DNA repair genes.
C)   increase mutation rates in microsatellite regions.
D)   are caused by mutations in DNA repair genes and increases mutation rates in microsatellite regions.
E)   are characterized by all of these traits.F) B) and E)
G) None of the above

Exam 12: Genes and Cancer

What is the role of oncogenes and tumor-suppressor genes, and how can mutations in these genes lead to cancer?

Correct Answer
Answered by ExamLex AI
Oncogenes and tumor-suppressor genes pla...
View Answer

The product of the RB tumor-suppressor gene is found in the cytoplasm.

Correct Answer
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The genetic model of colon cancer states that development of colo-rectal cancer requires only one key mutation.

Correct Answer
verified

It is estimated that 50 percent of all cancer deaths are related to behavior. Knowing the risks (and keeping in mind that you have a one in three chance of having cancer), do you feel inclined to alter your lifestyle to reduce your cancer risk? If so, what steps would you take? If not, why not?

Correct Answer
Answered by ExamLex AI
Yes, I would definitely feel inclined to...
View Answer

According to the American Cancer Society, 30 pecent of all cancer deaths is due to

Correct Answer
verified

Which one of the following statements about the BRCA1 gene for breast cancer is FALSE?

Correct Answer
verified

Specific aneuploidies are associated with various cancers.

Correct Answer
verified

Mutations that convert proto-oncogenes to oncogenes are mutations that cause

Correct Answer
verified

Individuals have different ____________________ to environmental agents that cause cancer.

Correct Answer
verified

Correct Answer
Answered by ExamLex AI
Retinoblastoma is a rare type of cancer ...
View Answer

The primary risk factor for cancer is ____________________.

Correct Answer
verified

The drug Gleevec is most closely associated with which of the following molecules?

Correct Answer
verified

Burkitt's lymphoma, chronic myelogenous leukemia, and many other leukemias are caused by chromosome ____________________.

Correct Answer
verified

Which of the following statements about retinoblastoma offers support for the idea that multiple mutations are needed in cancer?

Correct Answer
verified

Hereditary nonpolyposis colon cancers (HNPCC)

Correct Answer
verified

Which of the following is not a checkpoint in the cell cycle?

Correct Answer
verified

Exam 12: Genes and Cancer

What is the role of oncogenes and tumor-suppressor genes, and how can mutations in these genes lead to cancer?

Correct AnswerAnswered by ExamLex AIOncogenes and tumor-suppressor genes pla...View AnswerShow Answer

The product of the RB tumor-suppressor gene is found in the cytoplasm.

Correct AnswerverifiedShow Answer

The genetic model of colon cancer states that development of colo-rectal cancer requires only one key mutation.

Correct AnswerverifiedShow Answer

It is estimated that 50 percent of all cancer deaths are related to behavior. Knowing the risks (and keeping in mind that you have a one in three chance of having cancer), do you feel inclined to alter your lifestyle to reduce your cancer risk? If so, what steps would you take? If not, why not?

Correct AnswerAnswered by ExamLex AIYes, I would definitely feel inclined to...View AnswerShow Answer

According to the American Cancer Society, 30 pecent of all cancer deaths is due to

Correct AnswerverifiedShow Answer

Which one of the following statements about the BRCA1 gene for breast cancer is FALSE?

Correct AnswerverifiedShow Answer

Specific aneuploidies are associated with various cancers.

Correct AnswerverifiedShow Answer

Mutations that convert proto-oncogenes to oncogenes are mutations that cause

Correct AnswerverifiedShow Answer

Individuals have different ____________________ to environmental agents that cause cancer.

Correct AnswerverifiedShow Answer

Correct AnswerAnswered by ExamLex AIRetinoblastoma is a rare type of cancer ...View AnswerShow Answer

The primary risk factor for cancer is ____________________.

Correct AnswerverifiedShow Answer

The drug Gleevec is most closely associated with which of the following molecules?

Correct AnswerverifiedShow Answer

Burkitt's lymphoma, chronic myelogenous leukemia, and many other leukemias are caused by chromosome ____________________.

Correct AnswerverifiedShow Answer

Which of the following statements about retinoblastoma offers support for the idea that multiple mutations are needed in cancer?

Correct AnswerverifiedShow Answer

Hereditary nonpolyposis colon cancers (HNPCC)

Correct AnswerverifiedShow Answer

Which of the following is not a checkpoint in the cell cycle?

Correct AnswerverifiedShow Answer

Correct Answer
Answered by ExamLex AI
Oncogenes and tumor-suppressor genes pla...
View Answer

Correct Answer
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Correct Answer
verified

Correct Answer
Answered by ExamLex AI
Yes, I would definitely feel inclined to...
View Answer

Correct Answer
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Correct Answer
verified

Correct Answer
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Correct Answer
verified

Correct Answer
verified

Correct Answer
Answered by ExamLex AI
Retinoblastoma is a rare type of cancer ...
View Answer

Correct Answer
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Correct Answer
verified

Correct Answer
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Correct Answer
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Correct Answer
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Correct Answer
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