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Creutzfeldt-Jacob disease is known to have been transmitted by surgical instruments and transplanted nerve tissue.

A) True
B) False

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Most enveloped viruses use the host __________ membrane as their envelope source.


A) plasma
B) nuclear
C) mitochondrial
D) none of these

E) A) and B)
F) A) and C)

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A complete virus particle is called a


A) capsid.
B) nucleocapsid.
C) virion.
D) cell.

E) C) and D)
F) None of the above

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The production of cholera toxin by virulent strains of Vibrio cholera is dependent upon genes in a bacteriophage.This is an example of


A) lysogenic conversion.
B) induction.
C) bacterial transformation.
D) transduction.

E) A) and C)
F) A) and B)

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The simplest viruses consist of


A) RNA only.
B) Protein only.
C) RNA or DNA in a protein coat.
D) RNA or DNA in a protein coat covered with lipid envelope.
E) RNA,DNA and enzymes in a protein coat with a lipid envelope.

F) D) and E)
G) All of the above

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Adult T-cell leukemia is thought to be caused by


A) herpesviruses.
B) retroviruses.
C) parvoviruses.
D) picornaviruses.

E) A) and B)
F) None of the above

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The most common capsid morphologies are icosahedral and helical.

A) True
B) False

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Some complex viruses have icosahedral symmetry in the head region and helical symmetry in the tail.Overall,these viruses are said to have __________ symmetry.


A) bilateral
B) binal
C) complex
D) none of these

E) None of the above
F) A) and B)

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Viral capsids are generally constructed without any outside aid once the subunits have been synthesized.This process is called


A) facilitated assembly.
B) self-assembly.
C) spontaneous maturation.
D) self-maturation.

E) A) and D)
F) All of the above

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Enveloped viruses may enter their host cells by engulfment within coated vesicles (endocytosis).

A) True
B) False

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For a temperate phage to produce more phage,which of the following must happen?


A) Lysogeny
B) Induction
C) Lysogenic conversion
D) Prophage formation

E) All of the above
F) A) and B)

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Which of the following diseases is (are) caused by prions?


A) Scrapie
B) Mad cow disease
C) Kuru and Creutzfeldt-Jakob Disease
D) All of the choices are correct.

E) B) and C)
F) B) and D)

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The protein coat surrounding the viral genome is called the


A) capsule.
B) capsid.
C) matrix.
D) envelope.

E) A) and B)
F) All of the above

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Virion size ranges from


A) 1-40 nm.
B) 10-400 nm.
C) 600-1,000 nm.
D) 1,000-10,000 nm.

E) A) and D)
F) A) and C)

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Animal viruses have been cultivated in


A) suitable host animals.
B) embryonated eggs.
C) tissue cultures (monolayers of animal cells) .
D) All of the choices are correct.

E) A) and D)
F) C) and D)

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Which is not true of viruses?


A) They can exist in an intracellular or extracellular phase.
B) They infect animal and plant cells only.
C) They can be observed with an electron microscope.
D) They are acellular.
E) They replicate only inside host cells.

F) None of the above
G) A) and B)

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Viruses in the extracellular state possess few,if any,active enzymes.

A) True
B) False

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A __________ genome exists as several separate,nonidentical molecules that may be packaged together or separately.


A) diploid
B) segmented
C) polyploid
D) fractionated

E) A) and B)
F) A) and C)

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Which of the following is/are necessary for the replication of a satellite virus?


A) Host cell only
B) Helper virus only
C) Prion only
D) Host cell and helper virus

E) B) and C)
F) A) and C)

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The function of the viral protein coat is to


A) protect the viral genetic material.
B) aid in the transfer of the viral genetic material between host cells.
C) elicit the production of protective antibodies.
D) protect the viral genetic material and aid in the transfer of the viral genetic material between host cells.

E) A) and B)
F) All of the above

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