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Draw vertical lines through the peptide bonds in the decapeptide below that will be cleaved by cyanogen bromide. Try-Ser-Ala-Met-Ser-Pro-Met-Gly-Gly-Asp

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What is electrophoresis?


A) a technique that separates amino acids on the basis of their polarity
B) a technique that separates amino acids on the basis of their solubility in water
C) a technique that separates amino acids on the basis of their pI values
D) a technique that separates amino acids on the basis of pKa of α-COOH values
E) a technique that separates amino acids on the basis of pKa of α-+NH3 values

F) A) and C)
G) A) and B)

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Rate the following amino acids in decreasing order of migration towards the cathode (negative electrode)when separated by electrophoresis in a solution of pH= 7.3. I. lysine: pI= 9.87 II. alanine: pI= 6.02 III. aspartate: pI= 5.95

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Which of the following protein structures does denaturation destroy?


A) primary and secondary structures
B) secondary and tertiary structures
C) tertiary and quaternary structures
D) secondary, tertiary, and quaternary structures

E) None of the above
F) A) and B)

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Which of the following amino acids has the highest isoelectric point?


A) arginine
B) aspartic acid
C) glycine
D) proline
E) phenylalanine

F) A) and B)
G) C) and D)

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Which of the following best represents the structure of an amino acid in basic solution (pH = 11) ?


A) Which of the following best represents the structure of an amino acid in basic solution (pH = 11) ? A)    B)    C)    D)    E)
B) Which of the following best represents the structure of an amino acid in basic solution (pH = 11) ? A)    B)    C)    D)    E)
C) Which of the following best represents the structure of an amino acid in basic solution (pH = 11) ? A)    B)    C)    D)    E)
D) Which of the following best represents the structure of an amino acid in basic solution (pH = 11) ? A)    B)    C)    D)    E)
E) Which of the following best represents the structure of an amino acid in basic solution (pH = 11) ? A)    B)    C)    D)    E)

F) B) and C)
G) B) and D)

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What is the product obtained from the mild oxidation of the thiol shown below? mild 2 R-SH What is the product obtained from the mild oxidation of the thiol shown below? mild 2 R-SH   A) R-S-R B) R-OH C) R-S-S-R D) R-OO-R E) R-S-OH


A) R-S-R
B) R-OH
C) R-S-S-R
D) R-OO-R
E) R-S-OH

F) A) and B)
G) C) and D)

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Draw and name the amino acids which may be described as heterocyclic.

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Which of the following amino acids has a heterocyclic R group?


A) glycine
B) threonine
C) proline
D) aspartic acid
E) arginine

F) A) and E)
G) C) and E)

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Draw the dipeptide Val-Tyr at pH 7.0.

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Explain what is meant by kinetic resolution and give an example.

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A separation technique in which an enzym...

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Provide the structure of Thr-Gln-Met at pH 7.0.

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Which type of protein, globular or fibrous, tends to function primarily as structural parts of an organism?

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The monomeric units that make up peptides and protein polymers are ________.


A) nucleic acids
B) amino acids
C) oligosaccharides
D) amylopectins
E) celluloses

F) A) and B)
G) C) and D)

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Which of the following structures can polypeptides have?


A) primary structure
B) secondary structure
C) tertiary structure
D) quaternary structure
E) all of the above

F) A) and B)
G) B) and C)

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Draw glutamate.

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Describe what a β-pleated sheet is and explain the difference between parallel and anti-parallel β-pleated sheets.

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A β-pleated sheet is a type of secondary...

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Draw the form of L-tryptophan which is present at biological pH.

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Which of the following amino acids will be closest to the origin when separated by thin-layer chromatography? Which of the following amino acids will be closest to the origin when separated by thin-layer chromatography?   A) I B) II C) III D) IV E) V


A) I
B) II
C) III
D) IV
E) V

F) All of the above
G) D) and E)

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Draw the predominant form of aspartate at physiological pH.

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