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Researchers now believe most of the effects of moderate doses of ethanol:


A) result from cell membrane destabilization.
B) are similar to those produced by the general anesthetics.
C) are nonspecific and indirect.
D) result from specific actions at specific receptors.

E) B) and C)
F) B) and D)

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In alcohol withdrawal,the mood stabilizing drug Lamictal is efficacious in:


A) decreasing alcohol craving.
B) improving mood.
C) protecting the brain.
D) All of the answers are correct.

E) A) and B)
F) B) and C)

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As with many drugs of abuse,the positively reinforcing effects of ethanol are thought to be ultimately the result of the activation of the following neurotransmitter:


A) GABA.
B) glutamate.
C) acetylcholine.
D) dopamine.

E) B) and D)
F) A) and C)

Correct Answer

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The most common cause of death in alcoholics is:


A) respiratory arrest.
B) cardiac arrest.
C) stroke.
D) liver damage.

E) All of the above
F) B) and C)

Correct Answer

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Ethanol is metabolized in the ________ in its "first-pass metabolism."


A) liver
B) stomach
C) brain
D) small intestine

E) B) and C)
F) A) and B)

Correct Answer

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Tolerance to alcohol includes:


A) enzyme-induction (metabolic) and tissue/functional tolerance.
B) enzyme-induction (metabolic) but not tissue/functional tolerance.
C) tissue/functional but not enzyme-induction (metabolic) tolerance.
D) neither enzyme-induction (metabolic) nor tissue/functional tolerance.

E) A) and B)
F) A) and C)

Correct Answer

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Moderate doses of ethanol reduce the risk of ischemic stroke.

A) True
B) False

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At least part of ethanol's actions appear to be a result of alterations in serotonergic activity.

A) True
B) False

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Ethanol is soluble in fat,but not in water.

A) True
B) False

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Toluene,the psychoactive ingredient in airplane glue,exerts its central action through:


A) vasodilatation.
B) muscle relaxation.
C) activation of dopaminergic reward centers.
D) anesthetic-like effects.

E) None of the above
F) A) and C)

Correct Answer

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One of the mechanisms of ethanol action is activation of the NMDA subtype of the glutamate receptor.

A) True
B) False

Correct Answer

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Many of the effects of ethanol are believed to be due to:


A) enhancement of glutamate action at the NMDA receptor and blockade of GABA action.
B) enhancement of glutamate action at the NMDA receptor and enhancement of GABA action.
C) blockade of glutamate action at the NMDA receptor and enhancement of GABA action.
D) blockade of glutamate action at the NMDA receptor and blockade of GABA action.

E) B) and C)
F) None of the above

Correct Answer

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In expectant mothers,chronic ethanol ingestion but not binge drinking increases the risk of mental health problems in their children.

A) True
B) False

Correct Answer

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All of the following are believed to be mechanisms of action of moderate doses of ethanol,EXCEPT:


A) alterations of ACh receptor activity.
B) alterations of intracellular transduction processes.
C) alterations of NMDA receptor activity.
D) alterations of GABA receptor activity.

E) None of the above
F) A) and B)

Correct Answer

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