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The protein complex that activates progress through the M phase checkpoint will allow which of the following to occur?


A) cleavage of cohesin proteins by separase
B) modification of separase by cohesins
C) disassembly of spindle microtubules at the centromere
D) assembly of spindle microtubules

E) A) and B)
F) A) and C)

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What is produced if a cell completes mitosis but does not undergo cytokinesis?


A) two cells, one cell containing two nuclei and a second cell without a nucleus
B) two cells, each cell with half of the genetic material of the parent cell
C) two cells, each cell with an identical nucleus containing the genetic material of the parent cell
D) one cell with one nucleus containing half of the genetic material of the parent cell
E) one cell with two nuclei, each identical to the nucleus of the parent cell

F) All of the above
G) C) and D)

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Taxol is an anticancer drug extracted from the Pacific yew tree that binds to microtubules and prevents their depolymerization. Actively dividing cells treated with Taxol become blocked in which phase of mitosis?


A) prophase
B) prometaphase
C) metaphase
D) anaphase
E) telophase

F) A) and B)
G) None of the above

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Beginning with a fertilized egg (zygote) , a series of five cell divisions would produce an early embryo with how many cells?


A) 4
B) 8
C) 16
D) 32
E) 64

F) B) and C)
G) A) and D)

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Please use the following information to answer the question(s) below. Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can therefore be assayed to track their incorporation. In a set of experiments, a student-faculty research team introduced labeled T nucleotides into the culture of dividing human cells at specific times. -Which of the following questions might be answered by such a method?


A) How many cells are produced by the culture per hour?
B) What is the length of the S phase of the cell cycle?
C) When is the S chromosome synthesized?
D) How many picograms of DNA are made per cell cycle?
E) When do spindle fibers attach to chromosomes?

F) C) and D)
G) B) and E)

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  Figure 9.3 -In Figure 9.3, mitosis is represented by which numbered parts of the cycle? A)  I B)  II C)  III D)  IV E)  V Figure 9.3 -In Figure 9.3, mitosis is represented by which numbered parts of the cycle?


A) I
B) II
C) III
D) IV
E) V

F) A) and D)
G) A) and C)

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Why do neurons and some other specialized cells divide infrequently?


A) They no longer have active nuclei.
B) They no longer carry receptors for signal molecules.
C) They have been shunted into G0.
D) They no longer produce cyclins.

E) All of the above
F) C) and D)

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Through a microscope, you can see a cell plate beginning to develop across the middle of a cell and nuclei forming on either side of the cell plate. This cell is most likely


A) an animal cell in the process of cytokinesis.
B) a plant cell in the process of cytokinesis.
C) a bacterial cell dividing.
D) a plant cell in metaphase.

E) None of the above
F) A) and B)

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At which phase of mitosis do the sister chromatids become daughter chromosomes?


A) prophase
B) prometaphase
C) metaphase
D) anaphase
E) cytokinesis

F) A) and E)
G) A) and D)

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Please use the following information to answer the question(s) below. The unlettered circle at the top of Figure 9.1 shows a diploid nucleus with four chromosomes that have not yet replicated. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is black, and the other is gray. The circles labeled A-E show various combinations of these chromosomes. Please use the following information to answer the question(s)  below. The unlettered circle at the top of Figure 9.1 shows a diploid nucleus with four chromosomes that have not yet replicated. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is black, and the other is gray. The circles labeled A-E show various combinations of these chromosomes.   Figure 9.1 -What is the correct chromosomal condition for a nucleus in G1 of the cell division cycle? A)  A B)  B C)  C D)  D E)  E Figure 9.1 -What is the correct chromosomal condition for a nucleus in G1 of the cell division cycle?


A) A
B) B
C) C
D) D
E) E

F) A) and B)
G) A) and C)

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Which of the following is released by platelets in the vicinity of an injury?


A) PDGF
B) separase
C) protein kinase
D) cyclin

E) A) and B)
F) All of the above

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In the cells of some organisms, mitosis occurs without cytokinesis. This will result in


A) cells with more than one nucleus.
B) cells that are unusually small.
C) cells lacking nuclei.
D) cell cycles lacking an S phase.

E) B) and C)
F) A) and D)

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Where do the microtubules of the spindle originate during mitosis in animal cells?


A) centromere
B) centrosome
C) centriole
D) chromatid
E) kinetochore

F) All of the above
G) B) and E)

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When a cell is in late anaphase of mitosis, which of the following may be seen?


A) a clear area in the center of the dividing cell
B) decondensing chromosomes clustered at the poles
C) individual chromatids beginning to separate from one another
D) chromosomes clustered tightly at the center of the dividing cell
E) nuclear envelopes forming at the poles

F) A) and B)
G) C) and E)

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For a chemotherapeutic drug to be useful for treating cancer cells, which of the following is most desirable?


A) It is safe enough to limit all apoptosis.
B) It does not affect metabolically active cells.
C) It only attacks cells that are density dependent.
D) It targets only rapidly dividing cells.

E) B) and C)
F) A) and B)

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Movement of the chromosomes during anaphase would be most affected by a drug that prevents


A) nuclear envelope breakdown.
B) cell wall formation.
C) elongation of microtubules.
D) shortening of microtubules.
E) formation of a cleavage furrow.

F) A) and C)
G) A) and E)

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